image/svg+xml From Homeostasis to Allostasis Definition (Merriam Webster): For an organism: the maintenance of relatively stable internal physiological conditions (as body temperature or the pH of blood) in higher animals under fluctuating environmental conditionsMore generally: a relatively stable state of equilibrium or a tendency toward such a state between the different but interdependent elements or groups of elements of an organism, population, or group Definition (Bruce S. McEwen, Neurobiology of Aging, 2002): Allostasis is the process that keeps the organism alive and functioning, i.e. maintaining homeostasis or "maintaining stability through change" and promoting adaptation and coping, at least in the short run.(Peter Sterling and Joseph Eyer, 1988)"Homeostasis emphasized that the bodys internal environment is held constant by the self-correcting (negative feedback) actions of its constituent organs. Allostasis emphasizes that the internal milieu varies to meet perceived and anticipated demand. This variation is achieved by multiple, mutually reinforcing neural and neuroendocrine mechanisms that override the homeostatic mechanisms." Homeostasis in Braitenberg Vehicles Allostatic Control in a Synthetic Forager (Sanchez-Fibla et al., 2010) (The sims) Feedback control Plant /Process Proportional-Integral-Derivative controller(PID) Coupling Reactive Feedback with Adaptive Feed-Forward Control (Herreros et al., 2013) Adaptive control in the cerebellum Allostatic Control and Personality (Lallee et al., 2015) (Vouloutsi et al., 2013) EFAA project (2011-2014) WYSIWYD project (2014-2016) Back to Braitenberg
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  2. Homeostasis
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  13. Allostasis definition
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